Ocular therapies for neuronal ceroid lipofuscinoses: more than meets the eye

The neuronal ceroid lipofuscinoses（NCLs）,also known as Batten disease,are a group of inherited,neurodegenerative,lysosomal storage diseases typically manifesting in childhood.There are currently 13 known forms of NCL resulting from various mutations in the CLN（ceroid lipofuscinoses neuronal） genes（CLN1-8 and CLN10-14）.Although varying in onset and severity,