Distribution of Amniotic Epithelial Cells After Intraportal Infusion in a Rat Model

Miyako Tanaka,Kazuaki Tokodai, Masato Sato,Shuhei Yamada, Hitomi Okita,Takako Ito,Masatoshi Saito,Tetsuro Hoshiai,Shigehito Miyagi,Toshio Miki,Michiaki Unno,Takashi Kamei,Masafumi Goto

Transplantation Proceedings（2022）

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摘要

•hAECs accumulate only in the liver after intraportal cell infusion.•hAECs transplantation via the systemic circulation causes fatal pulmonary embolism.•hAECs transplantation via the spleen increases risk of thrombosis.•Intraportal infusion is promising for safe transplantation of hAECs in the liver.

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