Comparative Effectiveness of Transcutaneous Auricular Vagus Nerve Stimulation vs Citalopram for Major Depressive Disorder: A Randomized Trial

Shaoyuan Li,Peijing Rong,Yu Wang,Guixing Jin,Xiaobing Hou,Suxia Li,Xue Xiao,Wei Zhou, Yue Wu,Yaping Liu, Yue Zhang,Bin Zhao,Yiting Huang,Jin Cao,Helen Chen,Sierra Hodges,Mark Vangel,Jian Kong

Neuromodulation: Technology at the Neural Interface（2022）

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摘要

taVNS resulted in symptom improvement similar to that of citalopram; thus, taVNS should be considered as a therapeutic option in the multidisciplinary management of MDD. Nevertheless, owing to the design of this study, it cannot be ruled out that the reduction in depression severity in both treatment groups could be a placebo effect.

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关键词

Citalopram,depression,glutamate,major depressive disorder,transcutaneous auricular vagus nerve stimulation

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