Similar Clinical Improvement Rates among Biologic Drug Classes in Crohn’s Disease: Systematic Review and Meta-Regression

Jurij Hanzel,Rocio Sedano,Jenny Jeyarajah,Guangyong Zou,Stefanie C. McFarlane,Christopher Ma,Vipul Jairath

INFLAMMATORY BOWEL DISEASES（2022）

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摘要

Lay Summary We conducted a systematic review and metaregression of pivotal Crohn's disease trials to evaluate the rates of change in Crohn's Disease Activity Index scores in patients receiving biologic treatments. The speed of clinical improvement was similar among biologic drug classes.

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关键词

biologics,speed of improvement,randomized controlled trials

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