A Comparative Evaluation of Serum and Salivary Albumin in Normal, Gingivitis and Periodontitis Patients- A Clinico Biochemical Study

Aim: This study was designed to compare the salivary and serum albumin levels in healthy subjects, patients with gingivitis and chronic periodontitis. Materials and Methods: A total of 60 patients were selected and were divided into three groups (20 subjects each) as healthy, gingivitis and chronic periodontitis. Serum and saliva albumin level were recorded. The unstimulated whole saliva and blood samples from antecubital fossa were collected from the subjects. Bromocresol green method (BCG) used for estimation of both serum and salivary albumin. Results and Conclusion: The results of this study showed significant increase in serum albumin concentrations healthy and gingivitis subjects whereas salivary albumin was higher in gingivitis and periodontitis. Thus, serum albumin and salivaryalbumin concentration may aidin as an important biochemical indicator in assessing the severity of periodontitis. Keywords: Saliva, Albumin, Serum, Periodontitis, Gingivitis.