Autologous Hematopoietic Stem Cell Transplantation in Systemic Sclerosis Patientss

Systemic sclerosis (SScl) is an autoimmune disorder of unknown aetiology, characterised by ibrosis and microvascular injury of the affected organs.The hallmark of the disease is thickening and tightness of the skin and the subcutaneous tissue.SScl can affect virtually any organ systems, most importantly the skin, blood vessels, lungs, kidneys, gastrointestinal tract, and the heart [1].