Evaluation of Cardiac Function in a Knock-in Mouse Model for Human DCM at Early Postnatal Stages

Purpose：Dilated cardiomyopathy (DCM) is a most common cause of cardiac transplantation in children. However, little is known about the disease progression process of DCM in children. In this study, we explored the disease progression of DCM during early postnatal stages, using a knock-in mouse model for human DCM caused by ΔK210 mutation in the cardiac troponin T gene.