Comparison of Morphological and Histological Characteristics of Human and Sheep: Sheep as a Potential Model for Testing Midurethral Slings in vivo.

Ilaha Isali,Ahmad Osama Khalifa,Subba Shankar,Stanley Dannemiller,Walter Horne,Michelle Evancho-Chapman,Phillip McClellan,Gregory T MacLennan,Ozan Akkus,Adonis Hijaz

Urologia internationalis（2022）

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摘要

Sheep vaginal length is comparable to humans. Tissue integration and host response to PP slings showed chronic inflammation with rich collagen deposition around the material in both sheep and human specimens, highlighting the sheep as a potential animal model for preclinical testing of midurethral slings.

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关键词

Midurethral sling,Preclinical testing,Sheep model,Stress urinary incontinence

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