Splenic size as a marker for active inflammation in Crohn's disease

•Splenic volume depends on body habitus but can be affected by Crohn’s disease.•The follow-up of patients with Crohn's disease requires monitoring of the disease's activity.•Splenic volume varies and its enlargement might be a sign of disease relapse.•The ratio of splenic volume to BMI above 14 might be a sign of active phase of the disease.