Comparative Genomics and Characterization of SARS-CoV-2 P.1 (Gamma) Variant of Concern From Amazonas, Brazil.

Ricardo Ariel Zimerman,Patrícia Aline Gröhs Ferrareze,Flavio Adsuara Cadegiani,Carlos Gustavo Wambier, Daniel do Nascimento Fonseca, Andrea Roberto de Souza,Andy Goren,Liane Nanci Rotta, Zhihua Ren,Claudia Elizabeth Thompson

Frontiers in medicine（2022）

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摘要

P.1 has shown continuous evolution after its emergence. The lack of clear evidence for recombination and the positive selection demonstrated for several sites suggest that this lineage emergence resulted mainly from strong evolutionary forces and progressive accumulation of a favorable signature set of mutations.

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COVID-19,NSP,P.1,SARS-CoV-2,VOC,genomic epidemiology,phylogenomics,spike

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