Impressive and durable clinical responses obtained with dabrafenib and trametinib in low-grade serous ovarian cancer harbouring a BRAF V600E mutation
Gynecologic oncology reports(2022)
摘要
•LGSOC is characterized scarce therapeutic options in the advanced setting.•BRAF mutations are frequent on these types of tumours.•Dabrafenib/trametinib yield impressive responses in patients with BRAF mutations.
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关键词
Low-grade serous ovarian cancer,BRAF mutation,Dabrafenib,Trametinib,Combination treatment
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