Psychiatric Considerations in Pediatric Chronic Pain

Features| May 2021 Psychiatric Considerations in Pediatric Chronic Pain Souraya Torbey, MD; Souraya Torbey, MD Search for other works by this author on: This Site PubMed Google Scholar Gaëlle Rached, MD, MSc; Gaëlle Rached, MD, MSc Search for other works by this author on: This Site PubMed Google Scholar Dimitri Fiani; Dimitri Fiani Search for other works by this author on: This Site PubMed Google Scholar M-Irfan Suleman, MD, FAAP, FASA M-Irfan Suleman, MD, FAAP, FASA Search for other works by this author on: This Site PubMed Google Scholar ASA Monitor May 2021, Vol. 85, 25–26. https://doi.org/10.1097/01.ASM.0000751508.64877.83 Views Icon Views Article contents Figures & tables Video Audio Supplementary Data Share Icon Share Twitter LinkedIn Cite Icon Cite Get Permissions Search Site Citation Souraya Torbey, Gaëlle Rached, Dimitri Fiani, M-Irfan Suleman; Psychiatric Considerations in Pediatric Chronic Pain. ASA Monitor 2021; 85:25–26 doi: https://doi.org/10.1097/01.ASM.0000751508.64877.83 Download citation file: Ris (Zotero) Reference Manager EasyBib Bookends Mendeley Papers EndNote RefWorks BibTex toolbar search Search nav search search input Search input auto suggest search filter All ContentAll PublicationsASA Monitor Search Advanced Search Topics: chronic pain, pediatrics, psychiatry, pain Chronic pain can greatly affect a patient's daily functioning and significantly impact health-related quality of life (Pain 2005;119:1-4). Undertreated or untreated chronic pain in children can be especially burdensome to families by disrupting routines, restricting the child's daily activities, and increasing risk of long-term disability (Paediatr Drugs 2002;4:737-46). Therefore, it is not unusual for chronic pain to be highly comorbid with psychiatric disorders. This association is mediated by significant overlap in biological pathways. First, central and peripheral noradrenergic (NA) and serotoninergic (5-HT) pathways are affected in both pain and mood disorders (Prog Neuropsychopharmacol Biol Psychiatry 2018;87B:290-7; J Psychiatry Neurosci 2001;26:21-9). A pathway involving serotonergic neurons in the dorsal raphe nucleus has been implicated in chronic pain as well as depression (Nat Neurosci 2019;22:1612-4). Both NA and 5-HT brainstem-spinal descending systems... © 2021 American Society of Anesthesiologists (ASA), All Rights Reserved.2021 You do not currently have access to this content.