Candida albicans keratitis complicated with endophthalmitis after penetrating keratoplasty in Cogan's syndrome

A 30-year-old woman diagnosed of Cogan's syndrome (CS) with a chronic interstitial keratitis suffered from fungal keratitis and endophthalmitis after penetrating keratoplasty (PK). Microbiological cultures revealed a Candida albicans infection of the corneal graft. The corneoscleral rim was found out to be contaminated by this fungal species. Antifungal treatment, lensectomy and PK were performed. Fungal-related postoperative complications might be considered in a torpid postoperative course after PK specifically in immunosuppressed patients such CS. Routine corneoscleral rim culture may help to identify those patients who could benefit of prophylactic treatment.