Association of Serum Uric acid Level and BMI in NAFLD and Healthy Volunteers

A number of studies have reported that exact aetiology of non alcoholic fatty liver disease NAFLD is unknown. Serum uric acid is often incriminated as the etiological agent. Hence this study was taken up explore the role of BMI and serum uric acid in occurrence of NAFLD. A case control study was undertaken to compare the role of serum acid in occurrence of 100 NAFLD cases with 100 healthy volunteers. All the cases and controls were subjected for ultrasound examination and serum uric acid estimation with height and weight. Most of study subjects belonged to 21 – 40 years of age group and females outnumbered males. The Mean BMI among the cases was 25.34 (± 4.44) and controls was 25.12 (± 4.08). Mean serum uric acid level among the cases was 5.68 mg/dl and 4.14 mg/dl among the controls. BMI was more than 25 in 51% of the cases and 54% of the controls. Hyperurecemia was present in 37% of the NAFLD cases and 16% of the healthy volunteers. The author concludes that, the increased serum uric acid was demonstrated as risk factor for non alcoholic fatty liver disease.