Impact of Cernitin™ on induced chronic prostatitis in animal model for understanding management of lower urinary tract symptoms

•CernitinTM inhibit enzyme COX-2 and reduce the production of prostaglands which are known to cause pain during inflammation.•Simultaneously, CernitinTMtreatment may lead to recycling the AA to the cell membrane resulting in reduced AA release.•CernitinTM treatment inhibits conversion of testosterone to DHT, through inhibition of 5α-reductase enzyme.•Thus, decreasing AR/DHT interaction which ultimately leads to decrease proliferation and reduces PSA level.