Polyvalvular Heart Disease in Children Associated With FilaminA Mutations

Ellen S. Deng, Sarah B. Araten, Jessica M. Yamada,Michelle L. Walsh, Abbe Lai,Sangita Choudhury,Ming Chen

Circulation（2021）

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摘要

Introduction: FilaminA (FLNA), an X-linked gene encoding an actin binding protein, is one of the only known causative genes for periventricular nodular heterotopia (PVNH) and mitral valve (MV) prol...

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