Abstract 9487: Sildenafil (Viagra) Aggravates the Development of Experimental Abdominal Aortic Aneurysm

Chongyang Zhang,Amy Mohan,Hangchuan Shi,Chen Yan

Circulation（2021）

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Introduction: PDE5 plays a critical role in vascular smooth muscle cell (SMC) contraction by hydrolyzing 3’,5’ cyclic monophosphate (cGMP) and antagonizing cGMP-dependent protein kinase I (PKGI)-me...

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