1 H, 13 C, 15 N backbone and side-chain chemical shift assignments of the polyketide cyclase from Mycobacterium tuberculosis

Polyketide cyclase from Mycobacterium tuberculosis ( Mt PC) is related to the formation of sterol derivatives, which may play a role in immune escape in the initial stage of macrophage infection by Mycobacterium tuberculosis . However, the structure and specific functions of Mt PC are still unknown. Here we report the backbone and side-chain NMR resonance assignments for the Mt PC. Most resonances were assigned and the secondary structure was predicted according to the assigned backbone resonances by TALOS-N and PECAN. These NMR assignments represent a first step towards researching the structure and function of Mt PC.