Abstract 13132: The "Thrombosis-Bleeding Paradox" of Mechanical Circulatory Support: Shear Stress Promotes Platelet Prothrombosis and Microparticle Generation While Inducing Integrin αIIbβ3 Shedding and Decreased Aggregability
Circulation(2019)
摘要
Introduction: Mechanical circulatory support (MCS) has emerged as a lifesaving therapy for patients with advanced and end-stage heart failure. Sadly, MCS therapy is limited by a paradoxical coagulo...
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