Abstract 15685: Selective Improvement of Pulmonary Arterial Hypertension With Dual ETA/ETB Receptors Antagonist in the Apolipoprotein E-/- Model of PAH and Atherosclerosis

N Arnold,Laura West,Adam Braithwaite,Rachel E Walker, Mabrouka Alfaidi,Lewis Renshall,Janet Chamberlain, Helen Casbolt,Cathy M. Holt,Marc Iglarz,Sheila E. Francis,Allan Lawrie

Circulation（2016）

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Introduction: Pulmonary arterial hypertension (PAH) is a devastating condition and without treatment is associated with a life expectancy of 2.8 years. Apolipoprotein E deficient (ApoE-/-) mice dev...

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