THE LEVELS OF FOLIC ACID AND HOMOCYSTEINE IN THE BLOOD OF WOMEN WITH POLYCYSTIC OVARY SYNDROME AND THE DYNAMICS OF THESE INDICATORS DURING OF FOLATE THERAPY

It were examined 70 young women with PCOS. It was established, that these patients have lower levels of folic acid than healthy women, 47 % — reduction below reference values of norms, 52.8 % — hyperhomocysteinemia. Folic acid treatment at a dose of 5 mg/day helped to normalize its levels for 12 week therapy at that at women with normal body weight normalization was faster. The concentration of homocysteine during treatment as high as indicators of healthy women at patients with normal weight for 12 weeks of therapy, and at patients with obesity — for 24 weeks. Determination in blood levels of folate and homocysteine should be included a comprehensive examination of this category of patients, particularly at the stage pregravid period.