Prospective follow-up investigation for patients with post stroke depression

Objective To study the prevalence of depression at 2 weeks and 3 months after stroke and relevant factors of post stoke depression.Methods Two hundreds and fifty-seven patients with acute stroke were prospectively followed at 2 weeks and 3 months after stroke.Results Depressive rate 2 weeks after stroke was 32.59%,with a minor depression rate of 20.92%,and a major depression rate of 11.67%.Post stroke depression rate was 42.68% 3 months after stroke,including minor depression of 19.87% and major depression of 22.81%.Independent relevant factors for post stroke depression 2 weeks after stroke included introversion personality(P=0.000),diabetes(P=0.000),and severe neurologic impairment(P=0.000).Independent relevant factors for post stroke depression 3 months after stroke included depression diagnosed at the acute stage(P=0.000) and anterior circulation stroke(P=0.04).Conclusions Depression rate after stroke is high.Depression at 2 weeks after stroke is associated with introversion personality,severe neurologic impairment and diabetes.The independent relevant factors for depression at 3 months after stroke are depression diagnosed at the acute stage and anterior circulation stroke.