Microwave-Assisted Ring Expansion of N-Acetyl 3′-Unsubstituted Aziridine in the Presence of Lewis Acids.

Abstract The microwave-assisted ring expansion of N-acetyl 3′-unsubstituted aziridine-2-imides and N-acetyl 3′-unsubstituted aziridine-2-esters to oxazolines is reported. The regioselectivities of the rearrangements depend upon the reaction conditions, such as the Lewis acid selected and the solvent.