Study on the effect of immunoreaction of hepatitis b vaccine on students of jiao zuo city

[Objective]To investigate the effect of the hepatitis B vaccine on students and provide scientific evidence for preventing it.[Methods]A randomized sampling survey was carried out. A total of 1906 children,selected in four schools (two from elementary schools and two from junior high schools) from both city and countryside.[Results]The HB vaccine coverage rate in the city schools (98.89%) was higher than that in countries (96.62%). The anti-HBs positive rate was 58.5% in average and the HbsAg carrier rate was 2.62%. The non-response rate was 9.54% in average.[Conclusion]It suggests that the effect of hepatitis B vaccine was obvious,but the vaccination program should be strengthened in the countryside. To people with non-response,we should take measures to improve immunization level of anti-hepatitis B virus among them.