Punicalagin promotes autophagic degradation of human papillomavirus E6 and E7 proteins in cervical cancer through the ROS-JNK-BCL2 pathway

Xialin Xie,Liuyi Hu,Lulu Liu,Jiuru Wang,Yongai Liu,Li Ma,Guangying Sun,Changfei Li,Haji Akber Aisa,Songdong Meng

Translational Oncology（2022）

引用 6|浏览15

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摘要

•This study provides a novel insight into the mechanism of degradation of E6 and E7 caused by punicalagin-induced autophagy. Therefore, our results will offer new strategy for treatment of HPV-infected cervical cancer.

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关键词

Punicalagin,E6,E7,Cervical cancer,Autophagy

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