Eryloside F, a Novel Penasterol Disaccharide Possessing Potent Thrombin Receptor Antagonist Activity.

Paul Stead,Stephen Edward Hiscox,Phil S. Robinson,Nicholas B. Pike,Philip J. Sidebottom,Andrew D. Roberts,Nicholas L. Taylor,Amy E. Wright,Shirley A. Pomponi,David Langley

ChemInform（2000）

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摘要

We report the discovery of Eryloside F, a novel disaccharide of the steroidal carboxylic acid penasterol, isolated from an extract of the marine sponge Erylus formosus. The compound is a potent thrombin receptor antagonist, and furthermore inhibits human platelet aggregation in vitro.

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