Patient characteristics and antiseizure medication pathways in newly diagnosed epilepsy: Feasibility and pilot results using the common data model in a single-center electronic medical record database

•Comparisons of epilepsy treatment pathways are limited by available data standards.•The Common Data Model (CDM) offers an international clinical data sharing standard.•We validated a CDM phenotype to identify epilepsy in electronic health record data.•Levetiracetam replaced phenytoin as the most common first-line agent over time.•Significant variability persisted in first and subsequent antiseizure medication use.