Successful treatment with bortezomib for refractory fever associated with myelodysplastic syndrome with underlying lymphoplasmacytic lymphoma

Yotaro Motomura,Yoshihiro Umezawa,Tomoyuki Arimatsu,Keigo Okada,Osamu Miura,Takashi Kumagai

Clinical Case Reports（2022）

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摘要

We report a case of fever of unknown origin in a patient with MDS associated with IgM-MGUS. The patient was positive for MYD88 mutation, and chemotherapy for LPL/WM improved the fever. Analysis of MYD88 and the effect of chemotherapy on LPL/WM finally revealed the latent LPL/WM in this case.

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关键词

Lymphoplasmacytic lymphoma/Waldenstrom's macroglobulinemia,myelodysplastic syndrome,myeloid differentiation primary response 88

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