FACTORS ASSOCIATED WITH QUALITY OF LIFE IN PRE-DIALYSIS CHRONIC KIDNEY DISEASE PATIENTS, THAILAND

Health-related quality of life (QoL) has become an essential outcome measure for patients with chronic kidney disease CKD. People with CKD experience reduced QoL because of the high symptom and treatment burden. However, many factors can be improved to support QOL. This study aimed to assess QoL among pre-dialysis CKD patients in the Northeast of Thailand and determine the factors associated with their QOL using stratified random sampling to respond to a self-administered structured questionnaire. The multiple linear regression was performed to identify factors associated with quality of life. Moderate QoL (49.1%) was diagnosed in 347 pre-dialysis CKD patients. The multiple linear regression observed that factors associated with moderate QoL including depression (95%CI = 0.2.92,2.20; p < 0.001), income (95%CI = 0.00,0.00; p < 0.001), age (95%CI = -0.36-0.09; p = 0.001), sex (95%CI = -8.48-1.59; p = 0.004), co-disease (95%CI = -6.39-1.10; p = 0.006), and caregiver (95% CI = 0.56,13.16; p = 0.033), all variables can be predicted 049.3%. The findings indicate an issue that should be addressed to improve the patients’ QoL. Therefore, public health interventions should be developed and implemented to improve QoL among pre-dialysis CKD patients by focusing on older female patients with depression, low income, co-disease, and caregivers. These findings provided insight into several associations between pre-dialysis patient variables and their QoL. Healthcare providers should be aware of low QoL among elderly females with pre-dialysis chronic kidney disease, depression, low income, co-disease, and patients without caregivers to improve their quality of life.