Genomic profiles of vaccine breakthrough SARS-CoV-2 strains from Odisha, India

Arup Ghosh,Safal Walia,Roma Rattan,Amol Kanampalliwar,Atimukta Jha,Shifu Aggarwal,Sana Fatma,Niyati Das,Nirupama Chayani,Punit Prasad,Sunil K Raghav,Ajay Parida

International Journal of Infectious Diseases（2022）

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摘要

•Out of 36 samples, 33 reported symptomatic breakthrough infections•Predominant presence of T478K and L452R mutation in spike protein•The majority of the patients were infected with the Delta (B.1.617.2) variant•S:EFR156G substitution observed in 10 breakthrough cases•Only one case with comorbidities reported hospitalization

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Vaccine Breakthrough,COVID-19,SARS-CoV-2,Variants of Concern

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