Aluminum intake in the neonatal phase disrupts endochondral ossification in rodents

Mara Rubia Marques, Pedro Henrique Graciano de Assis, Patrícia Santos Azeredo, Jaqueline Aguiar Fleury,Janaina Ribeiro Costa,Liana Silva Gomes,Danilo Silva Lima, Naiara Cristina de Souza Ribeiro,Manoel Francisco Biancardi,Fernanda Cristina Alcântara Dos Santos

Journal of Trace Elements in Medicine and Biology（2022）

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摘要

•Aluminum intake during neonatal phase decreases bone mass.•Aluminun disrupts endochondral ossification during neonatal period.•Aluminum decreases bone architecture during the neonatal phase.•Aluminum affects bone collagen content.

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Al,FAO,MMP-2,Oc,PCNA,WHO

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