Differential Age-dependent Mechanisms of High-frequency Stimulation-induced Potentiation in the Prefrontal Cortex–Basolateral Amygdala Pathway Following Fear Extinction

Kuldeep Shrivastava,Rachel Schayek,Milly Kritman,Mouna Maroun

Neuroscience（2022）

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摘要

•LTP induction in the mPFC-BLA circuit following fear extinction is dissimilar in adult and PW rats.•Freezing levels during extinction positively correlated with the magnitude of LTP in adult rats only.•Synaptic changes following fear extinction are different in adult and PW rats.

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关键词

post-weanling,prefrontal cortex,amygdala,LTP,extinction

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