Strengthened and posterior-shifted structural rich-club organization in people who use cocaine

Shana A. Hall,Ryan P. Bell,Syam Gadde,Sheri L. Towe,Muhammad Tauseef Nadeem, Peter S. McCann,Allen W. Song,Christina S. Meade

Drug and Alcohol Dependence（2022）

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摘要

•People with cocaine use disorder (CUD) have increased structural rich club connectivity.•Rich club nodes are shifted to the posterior in CUD.•People with CUD have more rich-club and feeder edges, but fewer local edges than controls.•Rich-club abnormalities are related to lower clustering and striatal connectivity.•Rich-club abnormalities are associated with increased impulsivity in CUD.

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关键词

CUD,nRCC,BIS

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