Novel formulations of metal-organic frameworks for controlled drug delivery.

Although large numbers of MOFs have been developed as nanocarriers for drug delivery, further improvements are still needed to advance the application of MOFs in the clinic. For example, the circulation mechanism and degradation process of MOFs , the efficiency and pharmacokinetics of drugs , and the biological evaluation of MOFs in the controlled release of drugs. The present review work main focus on the recent progress of MOFs as effective nanocarriers for drug delivery and to examine some challenges and directions for its further clinical applications.