Neutralization of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Omicron and Other Variants in Serum From Children With Vaccination-Induced Myocarditis

Fatema Tuz Zahra,Gabrielle Grubbs,Kirsten Dummer,Adriana H. Tremoulet,Chisato Shimizu,Jane C. Burns,Surender Khurana

Clinical infectious diseases : an official publication of the Infectious Diseases Society of America（2022）

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摘要

Our study demonstrates that children who developed severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccination-induced myocarditis and may not receive another vaccination, could be susceptible to infection with Omicron and emerging variants. We observed higher neutralizing antibody titers in myocarditis patients vs. healthy vaccinated children, but significantly lower neutralization titers against Omicron in both groups.

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COVID-19, SARS-CoV-2, Omicron, vaccination, myocarditis

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