Antisense-mediated senseful regulation of orchestrated metabolic response
Cell Chemical Biology(2022)
摘要
Accumulation of fat in the liver predisposes affected individuals to a variety of diseases, yet the molecular mechanisms leading to steatosis still remain elusive. Matsushita et al. (2022) propose a novel mechanism that interconnects insulin resistance and fatty liver formation by an orchestrated regulation of Irs2 and its natural antisense transcript.
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