Monoamine oxidase A attenuates chondrocyte loss and extracellular matrix degradation in osteoarthritis by inducing autophagy

Ming Li,Zhibin Peng,Xiaokun Wang,Yansong Wang

International Immunopharmacology（2022）

引用 8|浏览2

暂无评分

摘要

•MAOA expression and autophagy markers was decreased in OA.•MAOA enhanced autophagy and inhibited ECM degradation in the OA rat model.•MAOA promoted autophagy and inhibited apoptosis of IL-1β-treated chondrocytes.•Restoring MAOA expression protected chondrocytes through autophagy regulation.

查看译文

关键词

Osteoarthritis,Autophagy,Extracellular matrix,MAOA,Chondrocyte

AI 理解论文

溯源树

样例

生成溯源树，研究论文发展脉络

Chat Paper

正在生成论文摘要