Changes in incidence rates of outcomes of interest in vaccine safety studies during the COVID-19 pandemic

Vaccine(2022)

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摘要
•Incidence rates of acute disseminated encephalomyelitis, EMEM, and TTP did not change significantly during the pandemic.•Rates of AMI, anaphylaxis, appendicitis, Bell’s palsy, convulsion/seizure, GBS, ITP, narcolepsy, stroke and VTE decreased.•Rates of Bell’s palsy, ITP and narcolepsy were higher in all settings than in in-person settings during the pandemic.•Future vaccine safety studies should consider including telehealth visits to identify Bell’s palsy, ITP and narcolepsy.
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关键词
COVID-19,Vaccine safety,Incidence rates,Telehealth,Difference in difference analyses
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