Neuropilin-1 is a valuable biomarker for predicting response of advanced non-small cell lung cancer patients to hypofractionated radiotherapy and PD-1 blockade

Pengyuan Kang,Yunfei Li,Zhi Hu,Ming Lei,Jun Cheng,Xiyuan Guo,Lulu Zhang,Sheng Lin,Qing Yuan

International Immunopharmacology（2022）

引用 2|浏览8

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摘要

•HFRT combined with PD1 blockade improves the outcome of NSCLC.•Elevated expression of NRP1 and TOX on T cells from patients with advanced NSCLC.•Reduced expression of NRP1 and TOX in peripheral CD8+ T cells indicates longer overall survival in NSCLC.

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关键词

Hypofractionated radiotherapy,Chemoimmunotherapy,NRP1,TOX

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