Pegylation of phenothiazine – A synthetic route towards potent anticancer drugs

Journal of Advanced Research(2022)

引用 11|浏览5
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摘要
•Antitumor activity of two PEGylated phenotiazines was investigated•The compounds showed cytotoxic activity against six tumor lines•They inhibited the tumor growth in experimental mice•The PEGylation improved the phenothiazine biocompatibility•A synergistic effect of PEG and phenothiazine toward properties improvement was proved
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关键词
Phenothiazine,Poly(ethylene glycol),Tumour growth inhibition
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