Pegylation of phenothiazine – A synthetic route towards potent anticancer drugs
Journal of Advanced Research(2022)
摘要
•Antitumor activity of two PEGylated phenotiazines was investigated•The compounds showed cytotoxic activity against six tumor lines•They inhibited the tumor growth in experimental mice•The PEGylation improved the phenothiazine biocompatibility•A synergistic effect of PEG and phenothiazine toward properties improvement was proved
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关键词
Phenothiazine,Poly(ethylene glycol),Tumour growth inhibition
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