Microwave assisted synthesis of rhodium(Ⅰ) N-heterocyclic carbene complexes and their cytotoxicity against tumor cell lines

Janina Schmidt, Jessica Wölker,Petra Lippmann,Ingo Ott

Journal of Organometallic Chemistry(2022)

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摘要
•[(COD)(NHC)RhCl] complexes can be conveniently prepared by microwave assisted synthesis.•[(COD)(NHC)RhCl] complexes trigger strong cytotoxic effects against cancer cells.•Isopropyl side chains at the nitrogen atoms of the NHC ligands are preferred over ethyl side chains.
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关键词
Bioorganometallic chemistry,Carbene,Cytotoxicity,Rhodium
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