Efficacy of the NS1-truncated live attenuated influenza virus vaccine for swine against infection with viruses of major North American and European H3N2 lineages

Elien Vandoorn,Anna Parys, Sharon Chepkwony,Koen Chiers,Kristien Van Reeth

Vaccine（2022）

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摘要

•NS1-truncated H3 swine influenza vaccine provides partial heterologous protection.•Mucosal and cellular immune responses likely play a key role in cross-protection.•Live vaccine might be beneficial for priming in a heterologous prime-boost regimen.

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关键词

Swine influenza A virus,H3N2,Live attenuated vaccine,NS1 truncation,Vaccine efficacy,Cross-protection

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