Reduced Left Hemisphere A1 MEG MMN Despite "Healthy" Scalp EEG MMN in First Episode Psychosis

Mismatch Negativity (MMN) is an auditory event-related potential reflecting the pre-attentive detection of novel non-predicted stimuli and is a biomarker of cortical dysfunction in schizophrenia (SZ). MMN to pitch (pMMN) and to duration (dMMN) deviant stimuli are impaired in chronic schizophrenia, but it is less clear if MMN is reduced in first episode schizophrenia.