Synergism Effect of Antibiotics and Silver Nanoparticles to Control Antibiotic Resistant Bacteria: A Mini Review

Antimicrobial resistance (AMR) is a serious threat to global public health. It causes the prevention and treatment of infectious diseases become more difficult, costly, and sometimes require toxic alternatives. One of the strategies to address this crisis is by developing new drugs formulation using nanoparticles (NPs). AgNPs widely known for its antibacterial activity and the synergism of AgNPs with antibiotic compound is reported to enhance its activity. Additionally, its activity is against the resistant bacteria. This review informs the advancement in AgNPs development and highlight the AgNPs antibacterial mechanism of action, and the synergistic effects of AgNPs-antibiotics.