The Minichromosome Maintainance Complex is Up-regulated in the Placentas of Low-Insulin Sensitive Mothers in the First Trimester of Pregnancy.
The FASEB journal(2022)
摘要
Low insulin sensitivity of pregnant women in in the early first trimester of pregnancy associated with obesity induced changes in the placental proteome related to DNA replication and cell cycle. This may reflect trophoblast response to increased DNA damage in these placentas.
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