Efficacy of post-injury anti-miR-181a and anti-miR-200c intravenous treatment in protection against experimental stroke in aged mice.

Both anti-miR-181a and anti-miR-200c are effective non-invasive post-stroke interventions to reduce injury in clinically-relevant aged mice. Future investigations should be extended to testing in aged female cohorts and identifying relevant downstream targets of miR-181a and miR-200c.