Predictors of Severe Outcome Following Opioid Intoxication in Children

Neta Cohen,Mathew Mathew,Adrienne Davis,Jeffrey Brent,Paul Wax,Suzanne Schuh,Stephen B Freedman,Blake Froberg,Evan Schwarz,Joshua Canning,Laura Tortora,Christopher Hoyte, Andrew L Koons,Michele M Burns, Joshua McFalls,Timothy J Wiegand,Robert G Hendrickson,Bryan Judge, Lawrence S Quang, Michael Hodgman, James A Chenoweth, Douglas A Algren,Jennifer Carey,E Martin Caravati,Peter Akpunonu, Ann-Jeannette Geib,Steven A Seifert,Ziad Kazzi,Rittirak Othong,Spencer C Greene,Christopher Holstege,Marit S Tweet,David Vearrier,Anthony F Pizon,Sharan L Campleman,Shao Li,Kim Aldy,Yaron Finkelstein

EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY（2022）

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摘要

Children with an opioid toxicity that have been exposed to fentanyl and those aged ≥10 years had 3.6 and 2.5 higher odds of ICU admission or death, respectively, than those without these characteristics. Prevention efforts should target these risk factors to mitigate poor outcomes in children with an opioid intoxication.

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关键词

Opioids,children,intoxication,poisoning

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