Synthesis and characterization of new Schiff-bases as Methicillin resistant Staphylococcus aureus (MRSA) inhibitors

Ratnamala S. Bendre,Rahul D. Patil,Pramod N. Patil,Harun M. Patel,Rakesh S. Sancheti

Journal of Molecular Structure（2022）

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摘要

•Design and synthesis of novel Schiff-bases using various heterocyclic amines.•Spectral characterization of all compounds.•In vitro, Anti-MRSA study with potential results.•Molecular docking with strong binding interactions with FabI enzyme of S. aureus.

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关键词

Schiff-base,Anti-MRSA,MIC and docking

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