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Antiulcer Activity of 3-Hydroxyimino Derivatives of Minor Triterpenoids of Licorice Root

Pharmaceutical chemistry journal(2022)

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摘要
3-Hydroxyimino derivatives of minor licorice triterpenoids possessed pronounced antiulcer activity and protected rat gastric mucosa from ulceration in indomethacin and orthophen ulcer models at a dose of 50 mg/kg. 3-Hydroxyimino-11-deoxoglycyrrhetic acid was the most active antiulcerogenic substance and was superior in activity to carbenoxolone.
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关键词
triterpenoids,licorice,oximes,antiulcer activity
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