Unexpected synthesis of benzimidazole from Schiff base mediated by lanthanide chloride and citotoxic activities
Journal of Molecular Structure(2022)
摘要
•Synthesis of the BenzHCl from Anisalophen with chloride lanthanide was carried out.•The mechanism of the reaction is proposed from different synthetic strategies.•The single-crystal X-ray structure of the BenzHCl is discussed.•Thermal stabilities of Anisalophen and BenzHCl were analyzed by TG/DTA techniques.•Cytotoxicity of compounds was investigated against HFibro, MCF7 and MDA-MB-231 cells.
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关键词
Benzimidazole,Schiff base,Lanthanide chloride,Reaction mechanism,Structure,Cytotoxicity
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